4.8 Article

Acridine-viologen dyads: Selective recognition of single-strand DNA through fluorescence enhancement

Journal

ORGANIC LETTERS
Volume 10, Issue 19, Pages 4295-4298

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol801731k

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Funding

  1. Council of Scientific and Industrial Research [NWP 0023]
  2. Department of Science and Technology, Government of India

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Tolylacridine-viologen dyads show distinct fluorescence emission changes in the presence of double-strand DNA (dsDNA) and single-strand DNA (ssDNA) depending on the position of the linkage. The para isomer shows fluorescence quenching in the presence of both dsDNA and ssDNA, while the ortho isomer interacts selectively with ssDNA with enhancement in fluorescence intensity.

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