4.8 Article

Two novel triterpenoids from Dysoxylum hainanense

Journal

ORGANIC LETTERS
Volume 10, Issue 19, Pages 4327-4330

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol801834y

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Funding

  1. Key Project of National Natural Science Foundation [30630072]
  2. Shanghai Municipal Scientific Foundation [06DZ22028]

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Two novel rearranged oleanane-type triterpenes, dysoxyhainanin A (1) possessing a unique 1,3-cyclo-2,3-seco A ring with a formamido-containing appendage and dysoxyhainanin B (2) featuring an unprecedented 1,2-dinor-3,10:9,10-bisseco skeleton, were isolated from Dysoxylum hainanense. Dysoxyhainanin A (1) exhibited significant antibacterial activity against Gram-positive bacteria.

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