4.8 Article

Synthetic studies toward pectenotoxin 2.: Part I.: Stereocontrolled access to the C10-C22 fragment

Journal

ORGANIC LETTERS
Volume 10, Issue 19, Pages 4179-4182

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol8015868

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Funding

  1. Helsinki University of Technology (Outstanding Junior Research Group Award)
  2. TEKES
  3. the Academy of Finland

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A highly stereocontrolled and efficient synthesis for a fully functionalized C-10-C-22 fragment of pectenotoxin 2 is described using a convergent sequence involving a stereoselective methylation of beta-hydroxyketone as a key step.

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