Journal
ORGANIC LETTERS
Volume 10, Issue 18, Pages 4029-4032Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801512q
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- The Region Ile-de-France
- Agence Nationale de la Recherche
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A copper-catalyzed direct alkenylation of oxazoles with bromoalkenes has been developed. The method is both regio- and stereoselective and tolerates a variety of functional groups. A wide range of 2-E-vinyl-substituted oxazoles were obtained in high yields including the highly fluorescent alkaloid annuloline.
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