4.8 Article

Terminal aziridines by α-deprotonation/electrophile trapping of N-protected aziridine

Journal

ORGANIC LETTERS
Volume 10, Issue 16, Pages 3453-3456

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol801224g

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N-tert-Butylsulfonyl and N-tert-butylsulfinyl aziridine undergo alpha-lithiation/electrophile trapping providing a new entry to terminal aziridines. With N-tert-butylsulfinyl aziridine complete asymmetric induction is observed a to nitrogen.

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