4.8 Article

Macrocyclic nonviral vectors: High cell transfection efficiency and low toxicity in a lower rim guanidinium calix[4]arene

Journal

ORGANIC LETTERS
Volume 10, Issue 18, Pages 3953-3956

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol801326d

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Funding

  1. Fondazione Cassa di Risparmio di Parma
  2. Ministero dell'Universita e della Ricerca (MUR) PRIN [2006034123]
  3. Centro Interdipartimentale Misure of the University of Parma

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New multivalent cationic lipids, one of them showing high efficiency and low toxicity in cell transfection, have been obtained by attaching guanidinium groups at the lower rim of calix[4]arenes.

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