Journal
ORGANIC LETTERS
Volume 10, Issue 24, Pages 5517-5520Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol802249z
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Funding
- NCET Foundation, NSFC [30725045]
- National 863 Program [2006AA02Z338]
- China Postdoctoral Science Foundation [20070410711]
- 973 program of China [2007CB507400]
- Shanghai Leading Academic Discipline Project [13906]
- Scientific Foundation of Shanghai China [07DZ19728, 06DZ19717, 06DZ19005]
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Ainsliatrimers A (1) and B (2), the first two guaianolide-type sesquiterpene lactone trimers, together with one new structurally related sesquiterpene dinner ainsliadimer B (3), were isolated from the aerial part of Ainsliaea fulvioides. Their structures were elucidated by spectroscopic techniques, including X-ray crystal diffraction. Both 1 and 2 showed potent cytotoxicites against LOVO and CEM cell lines.
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