Journal
ORGANIC LETTERS
Volume 10, Issue 16, Pages 3555-3558Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801313g
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A straightforward approach to macrocycles having four estrone-derived nuclei by the sequential Cu-catalyzed Huisgen azide-alkyne cycloaddition-Glaser-Eglington Cu homocoupling has been developed. Due to its efficiency and simplicity, this sequence is useful for application to different natural product scaffolds.
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