4.8 Article

Palladium-catalyzed three-component arylcyanation of internal alkynes-with aryl bromides and K4[Fe(CN)6]

Journal

ORGANIC LETTERS
Volume 10, Issue 5, Pages 901-904

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol703018t

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The one-pot, palladium-catalyzed, three-component coupling of aryl bromides, internal alkynes, and environmentally friendly K-4[Fe(CN)(6)] provides an efficient and direct method for the preparation of beta-arylalkenylnitriles.

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