4.8 Article

Aplaminal:: A novel cytotoxic aminal isolated from the sea hare Aplysia kurodai

Journal

ORGANIC LETTERS
Volume 10, Issue 3, Pages 489-491

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol7029307

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Aplaminal (1), a novel triazabicyclo[3.2.1]octane framework metabolite, has been isolated from the sea hare Aplysia kurodai. The structure was determined by analysis of NMR data and confirmed by single-crystal X-ray diffraction analysis. Aplaminal (1) exhibits cytotoxicity against Hela S-3 cells.

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