4.8 Article

A Versatile One-Pot Procedure to Phosphate Monoesters and Pyrophosphates Using Di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite

Journal

ORGANIC LETTERS
Volume 10, Issue 20, Pages 4461-4464

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol801608j

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Funding

  1. The Netherlands Organization for Scientific Research (NWO)

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A one-pot procedure for the preparation of phosphoramidates, phosphorothioates, pyrophosphates, phosphodiesters, and phosphofluoridates has been devised using di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite as the common phosphitylating reagent.

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