Journal
ORGANIC LETTERS
Volume 10, Issue 22, Pages 5219-5221Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol802218a
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Funding
- Asahi Glass Foundation
- Ministry of Education, Culture, Sports, Science and Technology, Japan [19205013]
- Japan Society for the Promotion of Science
- Grants-in-Aid for Scientific Research [19205013] Funding Source: KAKEN
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3-(2-Hydroxyphenyl)cyclobutanones react with aryl bromides in the presence of palladium catalysts to afford 4-arylmethyl-3,4-dihydrocoumarins in high yields through a sequence involving carbon-carbon bond cleavage and formation. In the case of the reaction with 2-(2-hydroxyphenyl)cyclobutanones, five- or seven-membered lactones were produced depending on the presence of an additional substituent at the 2-position.
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