4.8 Article

A new catalytic Cu(II)/Sparteine oxidant system for β,β-phenolic couplings of styrenyl phenols:: Synthesis of carpanone and unnatural analogs

Journal

ORGANIC LETTERS
Volume 10, Issue 18, Pages 4097-4100

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol801643t

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Funding

  1. Department of Pharamacology
  2. Vanderbilt University

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A new catalytic Cu(II)/sparteine system has been developed to promote beta,beta-phenolic couplings of styrenyl phenols en route to carpanone and related unnatural congeners in yields exceeding 85%.

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