Journal
ORGANIC LETTERS
Volume 10, Issue 2, Pages 285-288Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol702684d
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The ring-closing metathesis reaction has been successfully employed to form a range of dihydropyridone intermediates, which are in the correct oxidation state to undergo a base-induced elimination to reveal the aromatic 2-pyridone. This mild and novel approach to six-membered heteroaromatic compounds then provides access to a wide variety of substituted pyridines in excellent overall yield.
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