Journal
ORGANIC LETTERS
Volume 10, Issue 16, Pages 3489-3492Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801273x
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Highly functionalized cyclopentanes with four stereogenic carbons including two quaternary stereocenters have been synthesized in excellent yields (90-95%) with complete diastereoselectivities and excellent enantioselectivities (88-96% ee) by the organocatalyzed asymmetric domino Michael-Henry reaction.
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