Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 38, Pages 7050-7054Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob01882k
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Funding
- Thailand Research Fund, Mahidol University [IRN58W0005, BRG6180005]
- Center of Excellence for Innovation in Chemistry (PERCH-CIC)
- Office of the Higher Education Commission (Franco-Thai Cooperation Program in Higher Education and Research, PHC Siam 2017)
- Institute for the Promotion of Teaching Science and Technology and Science Achievement Scholarship of Thailand (SAST)
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A facile synthesis of various functionalized 3-substituted quinolin-2(1H)-ones through Ag(i) nitrate-catalyzed cyclization of o-alkynylisocyanobenzenes is described. The reaction allows rapid and convenient access to 3-substituted quinolin-2(1H)-one scaffolds in moderate to good yields.
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