4.6 Review

Recent advances in the synthesis of cyclopropanes

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 40, Pages 7315-7329

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob01187g

Keywords

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Funding

  1. National Key Research and Development Program of China [2016YFA0602900]
  2. National Natural Science Foundation of China [21472051, 21420102003]
  3. Guangdong Province Science Foundation [2017B090903003]

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Cyclopropanes, one of the most important strained rings, have gained much attention for more than a century because of their interesting and unique reactivity. They not only exist in many natural products, but have also been widely used in the fields of organic synthesis, medicinal chemistry and materials science as versatile building blocks. Based on the sustainable development in this area, this review mainly focuses on the recent advances in the synthesis of cyclopropanes classified by the type of catalytic system, including regio-, diastereo-, and enantio-selective reactions.

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