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Modulating glycosylation with exogenous nucleophiles: an overview

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 8, Pages 1184-1197

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob42129e

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Funding

  1. National Science Council (NSC) of Taiwan [NSC 102-2113M-009-009]
  2. Center for Interdisciplinary Science (CIS) of NCTU

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The major challenge in carbohydrate synthesis is stereochemical control of glycosidic bond formation. Different glycosylation methods have been developed that are based on the modulation effect of external nucleophiles. This review highlights the development, synthetic application, challenges and outlook of the modulated glycosylation methods.

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