Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 19, Pages 2993-3003Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob00032c
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Funding
- Engineering and Physical Sciences Research Council [EP/J000868/1, EP/H018034/1] Funding Source: researchfish
- EPSRC [EP/J000868/1, EP/H018034/1] Funding Source: UKRI
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Bimolecular nucleophilic substitution reactions of alcohols are fundamentally important transformations in organic chemistry yet, to date, they are relatively underdeveloped with respect to catalysis. This Article describes the emerging area of catalytic S(N)2 reactions with specific emphasis on the design and development of phosphorus(V) and cyclopropenone-based catalytic S(N)2 reactions of alcohols.
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