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Catalytic, enantioselective vinylogous Michael reactions

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 22, Pages 3531-3543

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob00332b

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Funding

  1. Deutsche Forschungsgemeinschaft [SCHN 441/10-1]
  2. Evonik Foundation

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Recent progress in the field of catalytic, enantioselective vinylogous Michael reactions of latent dienolates is described which furnish optically highly enriched chiral 1,7-dioxo compounds of great utility in one synthetic operation. Emphasis is given to new catalysis modes which realise this challenging transformation with high regio- as well as enantioselectivity.

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