Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 21, Pages 3344-3348Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob00451e
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- [25820404]
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Allosteric control of deoxyribozymes is useful for a broad range of practical applications, such as nucleic acid sensing and DNA-computing. We found that the catalytic activity of a DNA-hydrolyzing deoxyribozyme could be allosterically regulated by adding short oligonucleotides. We used this technique to construct deoxyribozyme-based logic gates.
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