Related references
Note: Only part of the references are listed.Synthesis and Structure-Activity Relationships of Indazole Arylsulfonamides as Allosteric CC-Chemokine Receptor 4 (CCR4) Antagonists
Panayiotis A. Procopiou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
A method for the regioselective synthesis of 1-alkyl-1H-indazoles
Han-Jun Liu et al.
TETRAHEDRON (2013)
Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study
Anthony Cahn et al.
BMC PHARMACOLOGY & TOXICOLOGY (2013)
Antagonism of human CC-chemokine receptor 4 can be achieved through three distinct binding sites on the receptor
Robert J. Slack et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2013)
Lead optimisation of the N1 substituent of a novel series of indazole arylsulfonamides as CCR4 antagonists and identification of a candidate for clinical investigation
Panayiotis A. Procopiou et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC chemokine receptor CCR4
R. J. Slack et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Chemokine Receptor Antagonists
James Pease et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Targeting chemokine receptors in chronic inflammatory diseases: An extensive review
Pim J. Koelink et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Antibody therapy for Adult T-cell leukemia-lymphoma
Takashi Ishida et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2011)
A Novel CC Chemokine Receptor 4 Antagonist RS-1269 Inhibits Ovalbumin-Induced Ear Swelling and Lipopolysaccharide-Induced Endotoxic Shock in Mice
Yasuhiro Nakagami et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2010)
RS-1748, a Novel CC Chemokine Receptor 4 Antagonist, Inhibits Ovalbumin-Induced Airway Inflammation in Guinea Pigs
Yasuhiro Nakagami et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2010)
Chemokine Receptor 4 Plays a Key Role in T Cell Recruitment into the Airways of Asthmatic Patients
Pandurangan Vijayanand et al.
JOURNAL OF IMMUNOLOGY (2010)
Intramolecular Hydrogen Bonding in Medicinal Chemistry
Bernd Kuhn et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Role of the Chemokine Receptors CCR1, CCR2 and CCR4 in the Pathogenesis of Experimental Dengue Infection in Mice
Rodrigo Guabiraba et al.
PLOS ONE (2010)
Potent and orally bioavailable CCR4 antagonists: Synthesis and structure-activity relationship study of 2-aminoquinazolines
Kazuhiro Yokoyama et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Synthesis of thiourea derivatives as CCR4 antagonists
Fang Zhao et al.
CHINESE CHEMICAL LETTERS (2009)
Novel CC chemokine receptor 4 antagonist RS-1154 inhibits ovalbumin-induced ear swelling in mice
Yasuhiro Nakagami et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
A universal approach to solvation modeling
Christopher J. Cramer et al.
ACCOUNTS OF CHEMICAL RESEARCH (2008)
Potent CCR4 antagonists: Synthesis, evaluation, and docking study of 2,4-diaminoquinazolines
Kazuhiro Yokoyama et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Performance of SM8 on a test to predict small-molecule solvation free energies
Adam C. Chamberlin et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2008)
Bipiperidinyl carboxylic acid amides as potent, selective, and functionally active CCR4 antagonists
Cyrille F. Kuhn et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2007)
Small molecule antagonists of the CC chemokine receptor 4 (CCR4)
Douglas F. Burdi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Core exploration in optimization of chemokine receptor CCR4 antagonists
Ashok V. Purandare et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
The road map to oral bioavailability: an industrial perspective
V. Hayden Thomas et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2006)
Optimization of 2-aminothiazole derivatives as CCR4 antagonists
XM Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Antagonists of CCR4 as immunomodulatory agents
Ashok V. Purandare et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
Genotoxic activities of aniline and its metabolites and their relationship to the carcinogenicity of aniline in the spleen of rats
EA Bomhard et al.
CRITICAL REVIEWS IN TOXICOLOGY (2005)
Chemokine receptors: Multifaceted therapeutic targets
AEI Proudfoot
NATURE REVIEWS IMMUNOLOGY (2002)
The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics
P Panina-Bordignon et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Allergen immunotherapy: current and new therapeutic strategies
JM Rolland et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2000)
Share Paper
