4.6 Article

Chemoselective and repetitive intermolecular cross-acyloin condensation reactions between a variety of aromatic and aliphatic aldehydes using a robust N-heterocyclic carbene catalyst

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 10, Pages 1547-1550

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob42486c

Keywords

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Funding

  1. NRF Nano Material Technology Development Program [2012M3A7B4049652]
  2. KETEP Human Resources Development Program [20124010203270]
  3. NRF Basic Science Research Program [2009-0094023]
  4. Korea Evaluation Institute of Industrial Technology (KEIT) [20124010203270] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  5. National Research Foundation of Korea [2012M3A7B4049652] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We found that chemoselectivity of the crossed acyloin product is controlled by the adjustment of the aromatic aldehyde/aliphatic aldehyde ratio. Moreover, we observed the persistent catalytic activity of the homogeneous NHC catalyst in a solution due to NHC catalyst robustness.

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