Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 11, Pages 1707-1710Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob41230j
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- Department of Defense [W9 11SR-08-C-0001]
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The chemical synthesis of staphyloferrin A, a siderophore used by Staphylococcus bacteria for ferric iron retrieval, has been achieved with 79% yield via solid phase peptide synthesis (SPPS). Biological activity of synthetic staphyloferrin A has been confirmed by demonstrating its capture and uptake by live S. aureus.
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