4.6 Article

Rhodium(III)-catalyzed C-H alkynylation of azomethine ylides under mild conditions

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 46, Pages 9329-9332

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob01596g

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Funding

  1. NSFC [21272231, 21402190, 21472186]
  2. Dalian Institute of Chemical Physics, Chinese Academy of Science

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Rh(III)-catalyzed efficient C-H alkynylation of azomethine imines with alkynylated hypervalent iodine is developed under mild conditions. A broad scope of azomethine imines and alkyne substrates is established. The azomethine acts as a masked aldehyde and circumvents its poor directing effect.

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