4.6 Article

Au(I)-catalyzed intramolecular oxidative cyclopropanation of 1,6-enynes derived from propiolamides with diphenyl sulfoxide

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 11, Issue 7, Pages 1089-1092

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob27394b

Keywords

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Funding

  1. National Research Foundation of Korea [NRF-2011-0023686, NRF-2012-015662]
  2. nano material technology development program [NRF-2012M3A7B4049653]
  3. National Research Foundation of Korea [2011-0023686, 2012M3A7B4049653, 2012R1A2A2A01015662] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We have developed gold(I)-catalyzed oxidative cyclopropanation of 1,6-enynes derived from propiolamides employing diphenyl sulfoxide as an oxidant. 1,6-Enynes having a terminal alkyne and a propiolamide tether efficiently transformed into cyclopropane carboxaldehyde derivatives.

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