Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 11, Issue 45, Pages 7830-7833Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob41558a
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Funding
- NSFC [21272174]
- Key Projects of Shanghai in Biomedicine [08431902700]
- Scientific Research Foundation of the State Education Ministry for Returned Overseas Chinese Scholars
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A highly regioselective halogenation of 2-substituted-1,2,3-triazoles was developed via sp(2) C-H activation. This method is compatible with halogen atoms, as well as electron-donating and electron-withdrawing groups. Meanwhile, the strategy is also efficient for the synthesis of a key intermediate of Suvorexant.
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