Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 11, Issue 37, Pages 6246-6249Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob41488d
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Funding
- National Natural Science Foundation of China [21272114, 90913023]
- National Natural Science Fund for Creative Research Groups [21121091]
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An efficient and selective Pd(0)-catalyzed sp(3) C-H bond arylation-oxidation of 4-methylquinazolines is reported. The method enables the introduction of arylketone at the benzylic position of 4-methylquinazolines without the use of an additional directing group, and atmospheric oxygen is used as the sole oxidant.
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