Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 11, Issue 4, Pages 545-548Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob27125g
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- MURST
- University La Sapienza, Rome
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Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.
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