Related references
Note: Only part of the references are listed.Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
Raphael Rodriguez et al.
NATURE CHEMICAL BIOLOGY (2012)
DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase
Katrin Paeschke et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands
Deepak Koirala et al.
NATURE CHEMISTRY (2011)
ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner
Martin J. Law et al.
CELL (2010)
Epigenetic Instability due to Defective Replication of Structured DNA
Peter Sarkies et al.
MOLECULAR CELL (2010)
Small-molecule-mediated G-quadruplex isolation from human cells
Sebastian Mueller et al.
NATURE CHEMISTRY (2010)
Alternative lengthening of telomeres: models, mechanisms and implications
Anthony J. Cesare et al.
NATURE REVIEWS GENETICS (2010)
A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells
Dennis Gomez et al.
NUCLEIC ACIDS RESEARCH (2010)
Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex
Anthony Bugaut et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines
Mallesham Bejugam et al.
ACS MEDICINAL CHEMISTRY LETTERS (2010)
Controlled-folding of a small molecule modulates DNA G-quadruplex recognition
Sebastian Mueller et al.
CHEMICAL COMMUNICATIONS (2009)
Isaindigotone Derivatives: A New Class of Highly Selective Ligands for Telomeric G-Quadruplex DNA
Jia-Heng Tan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Quinone Methides Tethered to Naphthalene Diimides as Selective G-Quadruplex Alkylating Agents
Marco Di Antonio et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway
Angela Rizzo et al.
NUCLEIC ACIDS RESEARCH (2009)
The G-Quadruplex Ligand Telomestatin Impairs Binding of Topoisomerase IIIα to G-Quadruplex-Forming Oligonucleotides and Uncaps Telomeres in ALT Cells
Nassima Temime-Smaali et al.
PLOS ONE (2009)
An Alternative DNA Structure Is Necessary for Pilin Antigenic Variation in Neisseria gonorrhoeae
Laty A. Cahoon et al.
SCIENCE (2009)
Accelerated senescence: An emerging role in tumor cell response to chemotherapy and radiation
David A. Gewirtz et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition
Zoe A. E. Waller et al.
CHEMICAL COMMUNICATIONS (2008)
Rational Design of Substituted Diarylureas: A Scaffold for Binding to G-Quadruplex Motifs
William C. Drewe et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres
Raphael Rodriguez et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Living on a break: cellular senescence as a DNA-damage response
Fabrizio d'Adda di Fagagna
NATURE REVIEWS CANCER (2008)
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: Diverse higher order DNA and RNA targets for cancer therapeutics
Dinshaw J. Patel et al.
NUCLEIC ACIDS RESEARCH (2007)
Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends
Claus M. Azzalin et al.
SCIENCE (2007)
Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: Small molecule regulation of c-kit oncogene expression
Mallesham Bejugam et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action
Anne De Cian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Macrocyclic and helical oligoamides as a new class of g-quadruplex ligands
Pravin S. Shirude et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
An RNA G-quadruplex in the 5′ UTR of the NRAS proto-oncogene modulates translation
Sunita Kumari et al.
NATURE CHEMICAL BIOLOGY (2007)
Highly efficient G-quadruplex recognition by bisquinolinium compounds
Anne De Cian et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
G-quadruplexes in promoters throughout the human genome
Julian L. Huppert et al.
NUCLEIC ACIDS RESEARCH (2007)
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells
Dennis Gomez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Oxazole-based peptide macrocycles: A new class of G-quadruplex binding ligands
Katja Jantos et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region
Jixun Dai et al.
NUCLEIC ACIDS RESEARCH (2006)
A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene
Himesh Fernando et al.
BIOCHEMISTRY (2006)
Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6-and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation
MJB Moore et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription
Susanna Cogoi et al.
NUCLEIC ACIDS RESEARCH (2006)
Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo
K Paeschke et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Shelterin: the protein complex that shapes and safeguards human telomeres
T de Lange
GENES & DEVELOPMENT (2005)
Putative DNA quadruplex formation within the human c-kit oncogene
S Rankin et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Prevalence of quadruplexes in the human genome
JL Huppert et al.
NUCLEIC ACIDS RESEARCH (2005)
Preferential binding of a G-quadruplex ligand to human chromosome ends
C Granotier et al.
NUCLEIC ACIDS RESEARCH (2005)
Interaction of telomestatin with the telomeric single-strand overhang
D Gomez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Propeller-type parallel-stranded g-quadruplexes in the human c-myc promoter
AT Phan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Halogen bonds in biological molecules
P Auffinger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
New pyridine carboxamide ligands and their complexation to copper(II). X-Ray crystal structures of mono-, di, tri- and tetranuclear copper complexes
SL Jain et al.
DALTON TRANSACTIONS (2004)
Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing
D Gomez et al.
NUCLEIC ACIDS RESEARCH (2004)
G-quartets 40 years later: From 5 '-GMP to molecular biology and supramolecular chemistry
JT Davis
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Biological activity of the G-quadruplex ligand RHPS4 (3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate) is associated with telomere capping alteration
C Leonetti et al.
MOLECULAR PHARMACOLOGY (2004)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
A Siddiqui-Jain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Crystal structure of parallel quadruplexes from human telomeric DNA
GN Parkinson et al.
NATURE (2002)
Telomere maintenance as a target for anticancer drug discovery
S Neidle et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular G-quadruplex
MY Kim et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
JF Riou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif
C Schaeffer et al.
EMBO JOURNAL (2001)
Telomere maintenance mechanisms as a target for drug development
DJ Bearss et al.
ONCOGENE (2000)