Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 31, Pages 6420-6431Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob25412c
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An efficient and general method for the synthesis of unsymmetrical tetrasubstituted ureas from carbamoylimidazole is described. The conversion is achieved by the concurrent quarternization of the imidazole nitrogen and activation of amines with AlMe3.
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