4.6 Article

α,β-Unsaturated imines via Ru-catalyzed coupling of allylic alcohols and amines

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 9, Pages 1746-1749

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob06921k

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Funding

  1. University of Wisconsin, Madison
  2. NSF [CHE-9208463, CHE-9629688]
  3. NIH [RR08389-01]

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A convenient synthesis of alpha,beta-unsaturated imines requiring only an allylic alcohol, an amine and a Ru catalyst has been developed. The use of large excesses of oxidant and the purification of sensitive intermediates can be avoided.

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