Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 24, Pages 4731-4738Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob25315a
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- CSIR, New Delhi
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The glucosamine derived glucoBOX-Cu(II) complex was found to be a unique catalytic system for enantioselective Friedel-Crafts alkylation of indoles with 2-enoylpyridine-1-oxides. A large number of 3-alkylated indole derivatives were prepared using 5 mol% glucoBOX-Cu(II) complex in excellent yields with high enantioselectivity up to 99% ee.
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