Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 9, Pages 1826-1833Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob05888f
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Funding
- Ministerio de Ciencia e Innovacion (Spain) [SUPRAMED CSD 2010-00065]
- Generalitat Valenciana [PROMETEO 2011/008]
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A Pd/C/Zn mixture with alcohols has been revealed to be an efficient transfer hydrogenation system to quinolines. Furthermore, the metals mixture is able to activate alcohols as N-alkylating agents in a hydrogen autotransfer process. 1,2,3,4-Tetrahydroquinolines and N-alkylated tetrahydroquinolines from quinolines have been obtained with excellent yields in one step.
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