4.6 Article

FeCl3 promoted highly regioselective [3+2] cycloaddition of dimethyl 2-vinyl and aryl cyclopropane-1,1-dicarboxylates with aryl isothiocyanates

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 26, Pages 5032-5035

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob25682g

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Funding

  1. Shanghai Pujiang Program [11PJ1411900]
  2. East China University of Science Technology
  3. China 111 Project [B07023]

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A FeCl3 promoted [3 + 2] annulation of dimethyl 2-vinyl and arylcyclopropane-1,1-dicarboxylate with aryl isothiocyanates has been developed to give pyrrolidine-2-thiones in good yields with high regioselectivity.

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