4.6 Article

The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 38, Pages 7649-7665

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob26082d

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The Kulinkovich cyclopropanation reaction provides a flexible and convenient method for the synthesis of cyclopropanols. Together with the diverse chemistry of the cyclopropanol unit, it offers access to a wide range of functionalised unsaturated and saturated compounds. The successful use in the synthesis of natural compounds is outlined in this perspective.

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