Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 6, Pages 1186-1195Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob06701j
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- University of Bari Aldo Moro
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A general procedure for the synthesis of the title compounds has been devised starting from the available 2-halophenylethyl azides, by means of click reactions with trimethylsilylacetylene or 1-trimethylsilyl-1,3-butadiyne followed by a transition metal-catalyzed functionalization of C-H bond. A further extension of this procedure led us to devise the synthesis of more complex 4,4'-bitriazole-fused dihydroisoquinolines.
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