Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 8, Pages 3041-3049Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00925c
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- North Carolina Biotechnology Center
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A pilot library of 2-aminoimidazole triazoles (2-AITs) was synthesized and assayed against Acinetobacter baumannii and methicillin-resistant Staphylococus aureus (MRSA). Results from these studies show that these new derivatives have improved biofilm dispersal activities as well as antibacterial properties against A. baumannii. With MRSA biofilms they are found to possess biofilm inhibition capabilities at low micromolar concentrations.
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