Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 15, Pages 5365-5368Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob05780d
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An efficient user-friendly method of acylation of Grignard reagents to selectively synthesize ketones is presented, which is assisted by simple amides such as NMP, or DMF. The present chemoselective method tolerates a variety of functional groups such as ketone, ester, nitrile and other functional groups.
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