Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 5, Pages 1474-1478Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00935k
Keywords
-
Categories
Funding
- French Ministry of Higher Education and Research (MESR)
Ask authors/readers for more resources
The reaction of 3-alkynyl-4-methoxycoumarins with molecular iodine in chlorinated solvents allows access to 3-iodofurochromones in good to excellent yields as the result of a iodocyclization-demethylation process. Competitive diiodination of the coumarin acetylene moiety could be eliminated by simply performing the reactions in refluxing 1,2-dichloroethane, owing to the thermal instability of the resulting (E)-1,2-diiodoethenylcoumarins.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available