Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 5, Pages 1342-1346Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00985g
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Funding
- National Natural Science Foundation of China [20572025, 20872037]
- Laboratory of Organic Functional Molecules, the Sino-French Institute of ECNU
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An efficient palladium/copper-catalyzed approach to the synthesis of highly substituted 3-formyl furans from the reactions of readily available alpha-bromoenaminones with terminal alkynes has been developed. This methodology was realized by the cascade reactions of Sonogashira coupling and the subsequent intramolecular cyclization.
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