Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 2, Pages 604-609Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00538j
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Two novel alkaloids, wilsoniamines A and B, both possessing a hexahydropyrrolo[1,2-c]imidazol-1-one ring system that has not previously been found in nature, together with a new alkaloid, amathamide H and a known alkaloid, amathamide C were isolated from the temperate Australian bryozoan, Amathia wilsoni. MS and NMR analysis established the structure of the new compounds and indicated that the structure of amathamide C and several related compounds be revised. Amathamides C and H showed moderate anti-malarial and anti-trypanosomal activity.
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