Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 15, Pages 5337-5342Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob05730h
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Funding
- Agence Nationale de la Recherche [ANR-09-BLAN-0081-01]
- Institut Universitaire de France (IUF)
- Quidd biotech company
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An easy and efficient solid-phase synthesis strategy to obtain rapidly water-soluble chromophores/fluorophores in highly pure form has been developed. This first successful use of N-Fmoc-alpha-sulfo-beta-alanine as a SPPS building block opens the way to the future development of promising direct on-resin peptide labelling and water-solubilising methods.
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