4.6 Article

A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 3, Pages 670-672

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00756k

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Funding

  1. National Science Council of the Republic of China

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2,7-Disubstituted pyrazolo[1,5-a]pyridines were synthesized in good chemical yields by the reaction of enediynones with hydrazine, followed by addition of copper chloride. This reaction can tolerate many functional groups.

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