Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 16, Pages 3627-3630Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c004344c
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Funding
- National Natural Science Foundation of China [30901858]
- National Key Tech Project for Major Creation of New Drugs [2009ZX09501-003]
- China Postdoctoral Science Foundation [20090461390]
- State Key Laboratory of Drug Research [SIMM1004KF-13]
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A new fluorescent turn-on probe for the rapid optical sensing of thiols has been designed and synthesized. The probe displays high on/off signal ratios and high selectivity towards thiols. The potential of the probe as a biosensor for thiols was demonstrated by imaging of thiols in living cells.
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