4.6 Article

Vinyl sulfone: a versatile function for simple bioconjugation and immobilization

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 3, Pages 667-675

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b920576d

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Funding

  1. Direccion General de Investigacion Cientifica y Tecnica (DGICYT) [CTQ2008-01754]
  2. Junta de Andalucia [P07-FQM-02899]
  3. University of Granada
  4. Spanish Ministerio de Educacion

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The easy functionalization of tags and solid supports with the vinyl sulfone function is a valuable tool in omic sciences that allows their coupling with the amine and thiol groups present in the proteogenic residues of proteins, in mild and green conditions compatible with their biological function.

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