Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 9, Pages 2052-2059Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b925845k
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- National Institutes of Health [GM72041]
- Robert A. Welch Foundation
- NATIONAL CENTER FOR RESEARCH RESOURCES [S10RR022532] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [P20GM072041] Funding Source: NIH RePORTER
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Five new water-soluble derivatives of Nile Red 1-5 were prepared. These benzophenoxazine dyes fluoresce between 640 and 667 nm with quantum yields of 0.17-0.33 in pH 7.4 phosphate buffer, and at slightly shorter wavelengths and higher quantum yields in EtOH. Two dyes, 3 and 4 permeated into Clone 9 cells and selectively stained mitochondria and golgi, respectively.
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