4.6 Article

Ligand-free copper(I)-catalysed intramolecular direct C-H functionalization of azoles

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 4, Pages 841-845

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b916549e

Keywords

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Funding

  1. University of the Basque Country/Basque Government [S-PC08UN04, UNESCO07/08, GIU06/87/IT-349-07]
  2. Spanish Ministry of Education and Science

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The first examples of copper-catalysed intramolecular direct C-arylation of azaheterocycles for the synthesis of complex heterofused compounds is presented, featuring an unprecedented arylation via C-H activation of 9H-purine and 4-azabenzimidazole.

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