Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 12, Pages 2814-2822Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c001479f
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Funding
- North Carolina Biotechnology Center [2008-MRG-1114]
- V foundation
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A library of 4,5-disubstituted-2-aminoimidazoles was synthesized using a nitroenolate route and then screened for antibiofilm and antimicrobial activity. These compounds displayed notable biofilm dispersal and planktonic microbicidal activity against various Gram-positive and Gram-negative bacteria.
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