Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 6, Pages 1351-1360Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b920535g
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Funding
- BBSRC
- Wellcome Trust
- Royal Society
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Sugars and simplified oligosaccharide mimics can be joined with protein fragments at pre-defined sites using reliable chemical reactions such as thiol alkylation and Cu(I) catalysed azide/acetylene ligation (click chemistry). These fragments have the potential to be assembled into neoglycoprotein therapeutics using native chemical ligation.
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